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Is low dietary intake of omega-3 fatty acids associated with depression?

Hakkarainen R, Partonen T, Haukka J, Virtamo J, Albanes D, Lönnqvist J.

Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland. reeta.hakkarainen@ktl.fi

OBJECTIVE: This study examined the association between the dietary intake of omega-3 fatty acids and low mood, major depression, and suicide. METHOD: A total of 29,133 men ages 50 to 69 years participated in a population-based trial in Finland. The intake of fatty acids and fish consumption were calculated from a diet history questionnaire. Self-reported depressed mood was recorded three times annually, data on hospital treatments due to a major depressive disorder were derived from the National Hospital Discharge Register, and suicides were identified from death certificates. RESULTS: There were no associations between the dietary intake of omega-3 fatty acids or fish consumption and depressed mood, major depressive episodes, or suicide. CONCLUSIONS: Dietary intake of omega-3 fatty acids showed no association with low mood level.

PMID: 14992986 [PubMed - indexed for MEDLINE]