The four diagrams show the key-changes in skeletal muscle phospholipid fatty acid composition during a period of weight stabilization following a VLCD. Concentration of long-chain polyunsaturated fatty acids of the n-3 class (LCPUFAn-3) increased due to increased eicosapentaenoic acid (EPA, C20:5n-3) and docosahexaenoic acid (DHA, C22:6n-3); also the ratio of LCPUFA of the n-3 class versus the n-6 class increased. Data are Mean +/- SEM. White bars give data obtained at the end of the VLCD period (baseline) and black bars give data obtained 24 weeks later during the weight maintenance period. *, P < 0.05; **, P < 0.01.
Haugaard et al. Lipids in Health and Disease 2009 8:34 doi:10.1186/1476-511X-8-34