Table 1

Lipoprotein subclass measurements and physiological variables at baseline by case/control status

Variable

Controls (n = 73)

Participants (n = 73)

p valuea


Lipoprotein subclassb

VLDL and chylomicron particle concentrations (nmol/L)

Total VLDL and chylomicron particles

82.0 ± 45.3

87.5 ± 39.6

0.15

Large VLDL and chylomicron particles

4.6 ± 6.3

8.2 ± 6.8

< 0.01c

Medium VLDL particles

38.1 ± 28.5

39.7 ± 25.7

0.50c

Small VLDL particles

39.3 ± 19.9

39.7 ± 17.2

0.90

LDL particle concentrations (nmol/L)

Total LDL particles

1253 ± 367

1437 ± 477

0.01

Large LDL particles

337 ± 211

251 ± 218

< 0.01c

Intermediate LDL particles

45.8 ± 38.5

72.6 ± 50.2

< 0.01c

Small LDL particles

870 ± 434

1113 ± 478

< 0.01

HDL particle concentrations (μmol/L)

Total HDL particles

34.7 ± 6.7

32.1 ± 5.6

0.01

Large HDL particles

6.4 ± 3.5

4.6 ± 3.4

< 0.01

Medium HDL particles

5.2 ± 4.9

5.9 ± 4.8

0.25c

Small HDL particles

23.1 ± 7.0

21.7 ± 5.8

0.17

Mean particle sizes (nm)

VLDL size

50.6 ± 9.0

55.6 ± 10.4

< 0.01

LDL size

20.7 ± 0.9

20.2 ± 0.8

< 0.01

HDL size

8.9 ± 0.4

8.6 ± 0.3

< 0.01

Physiological variablesd

Age

60.0 ± 7.8

60.3 ± 8.0

0.79

Body mass index (kg/m2)

28.2 ± 3.7

34.0 ± 7.0

< 0.01

Systolic blood pressure (mm Hg)

133 ± 17

136 ± 17

0.12c

Diastolic blood pressure (mm Hg)

78.9 ± 9.2

80.8 ± 9.8

0.50c

HDL-cholesterol (mg/dl)

50.5 ± 13.7

43.7 ± 13.1

< 0.01c

LDL-cholesterol (mg/dl)

111 ± 33

111 ± 39

0.64c

Total cholesterol (mg/dl)

191 ± 42

193 ± 47

0.82

Triglycerides (mg/dl)

148 ± 100

189 ± 99

< 0.01

Physical fitness (Bruce score)

10.4 ± 2.8

6.6 ± 2.2

< 0.01

Framingham risk (× 100)

7.4 ± 6.8

10.7 ± 8.5

0.02c


Values are presented as mean ± SD. a: tested by independent samples Student-t test, b: there was no missing data, c: tested by a nonparametric Mann-Whitney U test because data was not normally distributed after LN transformation, d: there was < 3.2% missing data.

Decewicz et al. Lipids in Health and Disease 2009 8:26   doi:10.1186/1476-511X-8-26

Open Data