Table 2 |
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|
Findings of linkage analysis. |
||||
| Analysis Method |
Whole data (ASPs = 190) |
Subset Data (Positive LOD score families) (ASPs = 77) |
||
|
|
||||
| Sac1 LOD score (P value) |
-75G>A |
+83C>T |
||
|
|
||||
| Multipoint Linkage analysis |
NS |
7.42 (<0.001) |
||
| Single Point Linkage |
NS |
4.49 (<0.0001) |
2.77 (0.0002) |
NS |
| IBD Pi (P value) |
NS |
Pi 0.59 (<0.0001) |
Pi 0.56 (<0.0001) |
Pi 0.52 (0.0012) |
| QTL |
NS |
TC 1.42 (0.005) HDL-c 1.72 (0.002) ApoB 1.19 (0.010) |
NS |
NS |
|
ASPs, Affected sib pairs; IBD, identity by descent; Pi, mean proportion of allele sharing; NS, Not significant, QTL, Quantitative trait loci. | ||||
Shanker et al. Lipids in Health and Disease 2008 7:33 doi:10.1186/1476-511X-7-33 |
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