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The effect of ProAlgaZyme on various parameters related to metabolic syndrome. Bolded values represent mean Δ after 10* weeks of treatment ± (1.96*SEM) for a 95% confidence level. Values in parentheses are mean starting values (at T = 0) ± (1.96*SEM). Significance indicates comparison of changes after 10* weeks of treatment with PAZ to placebo. A negative value indicates a decrease, while a positive value indicates an increase over the test period. *Values for RBC sedimentation, triglycerides, LDL-C and blood pressure are after 8 weeks of treatment. NS = Not significant. |
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| Parameters |
Δ ProAlgaZyme (T = 0) |
Δ Placebo (T = 0) |
Significance |
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| Weight (kg) |
-4.18 ± 0.76 (86.70 ± 2.31) |
-1.20 ± 0.29 (86.34 ± 2.61) |
P < 0.001 |
| BMI (kg/m2) |
-1.51 ± 0.28 (31.13 ± 0.62) |
-0.20 ± 0.11 (31.95 ± 0.63) |
P < 0.001 |
| Body fat (%) |
-2.46 ± 3.51 (40.14 ± 0.79) |
-0.30 ± 0.17 (41.88 ± 1.11) |
P < 0.001 |
| Blood pressure (Sys8, mm Hg) |
-10.32 ± 2.69 (152.23 ± 4.41) |
-1.36 ± 2.18 (158.21 ± 4.39) |
P < 0.01 |
| Blood pressure (Dias8, mm Hg) |
-7.27 ± 2.50 (68.73 ± 2.58) |
-2.32 ± 1.84 (72.82 ± 2.69) |
P < 0.001 |
| Insulin (uIU/mL) |
1.28 ± 2.34 (23.48 ± 2.23) |
-1.01 ± 1.57 (23.02 ± 3.18) |
NS |
| Fasting blood glucose (mg/dL) |
-18.50 ± 5.56 (98.72 ± 5.65) |
-0.58 ± 2.11 (98.41 ± 3.41) |
P < 0.001 |
| Total cholesterol (mg/dL) |
-64.84 ± 9.68 (201.94 ± 3.92) |
-5.45 ± 2.51 (204.17 ± 3.87) |
P < 0.001 |
| HDL cholesterol (mg/dL) |
15.37 ± 3.04 (37.02 ± 1.07) |
-2.98 ± 1.53 (38.76 ± 1.44) |
P < 0.001 |
| LDL cholesterol8 (mg/dL) |
-40.63 ± 9.58 (131.32 ± 3.73) |
-0.69 ± 2.79 (131.45 ± 4.15) |
P < 0.001 |
| Triglycerides8 (mg/dL) |
-18.77 ± 6.18 (167.95 ± 7.35) |
-1.96 ± 4.52 (166.67 ± 4.64) |
P < 0.001 |
| RBC sed. rate8 (mm/h) |
-3.05 ± 0.78 (14.23 ± 0.58) |
-0.25 ± 0.65 (14.36 ± 0.68) |
P < 0.001 |
| C-reactive protein (mg/L) |
-6.20 ± 0.92 (10.83 ± 0.51) |
-0.83 ± 0.49 (11.41 ± 0.67) |
P < 0.001 |
| Interleukin-6 (pg/mL) |
-3.62 ± 1.03 (14.40 ± 2.01) |
-0.03 ± 0.26 (12.65 ± 1.20) |
P < 0.001 |
| TNF-a (pg/mL) |
-0.65 ± 0.66 (11.22 ± 1.14) |
-0.08 ± 0.44 (10.95 ± 0.84) |
P < 0.05 |
Oben et al. Lipids in Health and Disease 2007 6:20 doi:10.1186/1476-511X-6-20 |
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