Table 3 |
|
|
Mechanisms mediating the anti-atherosclerotic effect of nitric oxide |
|
| Anti-atherosclerotic effect of nitric oxide |
Reference(s) |
|
|
|
| Promotion of SMC proliferation |
131 |
| Inhibition of platelet aggregation |
132 |
| Reduction in endothelial activation & Inhibition of MCP-1 |
133, 134 |
| Stabilizes NF-Kβ inhibitor, Ikβα |
135 |
| Inhibition of LDL oxidation & lipid peroxidation |
136,137 |
| Reduces super oxide generation |
138 |
| Decrease the Expression of PAI-1 |
34 |
| Nitric oxide regulates vascular cell adhesion molecule 1 gene expression |
139 |
Sharma et al. Lipids in Health and Disease 2006 5:1 doi:10.1186/1476-511X-5-1 |
|