Table 3

Mechanisms mediating the anti-atherosclerotic effect of nitric oxide

Anti-atherosclerotic effect of nitric oxide
Reference(s)

Promotion of SMC proliferation
131
Inhibition of platelet aggregation
132
Reduction in endothelial activation & Inhibition of MCP-1
133, 134
Stabilizes NF-Kβ inhibitor, Ikβα
135
Inhibition of LDL oxidation & lipid peroxidation
136,137
Reduces super oxide generation
138
Decrease the Expression of PAI-1
34
Nitric oxide regulates vascular cell adhesion molecule 1 gene expression
139

Sharma et al. Lipids in Health and Disease 2006 5:1   doi:10.1186/1476-511X-5-1

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