|
Kinetic parameters of LDL, LDL + HDL2 and LDL + HDL3 oxidation in 59 healthy subjects. |
|||
| Women |
Men |
All |
|
|
|
|||
| LDL |
|||
| Lag time (min) |
60.9 ± 7.9 |
59.3 ± 6.9 |
60.2 ± 7.4 |
| Rate (μmol/l/min)a |
0.509 ± 0.067 |
0.502 ± 0.067 |
0.506 ± 0.066 |
| Max (nmol/mg)b |
541 ± 41 |
537 ± 51 |
539 ± 45 |
| LDL + HDL2 |
|||
| Lag time (min) |
56.0 ± 5.7*** |
56.0 ± 6.7*** |
56.0 ± 6.1*** |
| Rate (μmol/l/min)a |
0.687 ± 0.062*** |
0.654 ± 0.084*** |
0.671 ± 0.073*** |
| Max (nmol/mg)b |
774 ± 40*** |
745 ± 71*** |
762 ± 56*** |
| LDL + HDL3 |
|||
| Lag time (min) |
55.8 ± 5.4*** |
54.8 ± 5.4*** |
55.3 ± 5.4*** |
| Rate (μmol/l/min)a |
0.616 ± 0.064*** |
0.607 ± 0.070*** |
0.612 ± 0.066*** |
| Max (nmol/mg)b |
687 ± 40*** |
674 ± 60*** |
681 ± 50*** |
|
Values are mean ± SD. a Rate means maximal formation rate of conjugated dienes during oxidation. Calculation of the diene concentration is based on ε = 29500 of the conjugated dienes b Max is the maximal amount of dienes produced per mg of LDL protein. *** p < 0.001 in comparison with LDL alone in Wilcoxon's matched pairs test. | |||
Solakivi et al. Lipids in Health and Disease 2005 4:25 doi:10.1186/1476-511X-4-25 |
|||