|
Effect of pyridoxine on the fatty acid composition in erythrocyte membranes |
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| Days of treatment |
||||
| Fatty acid |
Basal 1 |
30 |
60 |
Basal 2 |
|
|
||||
| 16:0 |
22.0 ± 1.0a |
19.0 ± 1.3a |
17.0 ± 1.4b |
23.8 ± 0.9a |
| 16:1 |
0.3 ± 0.05a |
1.0 ± 0.2b |
1.0 ± 0.1b |
1.3 ± 0.2b |
| 18:0 |
20.4 ± 0.3a |
22.0 ± 0.5b |
23.0 ± 0.4b |
19.3 ± 0.2c |
| 18:1 |
14.7 ± 0.4 |
14.3 ± 0.5 |
14.7 ± 1.3 |
14.2 ± 0.6 |
| 18:2 n-6 |
10.7 ± 0.4 |
11.0 ± 0.5 |
10.5 ± 1.0 |
10.6 ± 0.5 |
| 20:3 n-6 |
1.9 ± 0.1 |
1.6 ± 0.1 |
2.1 ± 0.2 |
1.6 ± 0.1 |
| 20:4 n-6 |
19.4 ± 0.9a |
19.0 ± 0.7a |
20.6 ± 0.7a |
15.7 ± 0.7b |
| 22:4 n-6 |
0.5 ± 0.1a |
0.4 ± 0.05a |
0.5 ± 0.1a |
0.2 ± 0.02b |
| 22:5 n-6 |
4.7 ± 0.5 |
4.1 ± 0.3 |
4.7 ± 0.3 |
3.5 ± 0.2 |
| 22:5 n-3 |
2.6 ± 0.2a |
2.3 ± 0.2ab |
2.6 ± 0.2a |
1.9 ± 0.1b |
| 22:6 n-3 |
4.7 ± 0.3 |
5.6 ± 0.5 |
5.0 ± 0.5 |
4.2 ± 0.3 |
|
Results are the means of 12 determinations ± 1 SEM expressed as μg % of total fatty acids. Fatty acids are identified by: number of carbon atoms in the chain is given first, value following the colon represents number of double bonds (zero means saturated fatty acid); number following n- indicates the position of the last double bond counting the double bond from the terminal methyl group. Values not bearing the same superscript letter are significantly different at P < 0.05. | ||||
de Gómez Dumm et al. Lipids in Health and Disease 2003 2:7 doi:10.1186/1476-511X-2-7 |
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