Table 2

Effect of pyridoxine on the fatty acid composition in erythrocyte membranes



Days of treatment

Fatty acid
Basal 1
30
60
Basal 2

16:0
22.0 ± 1.0a
19.0 ± 1.3a
17.0 ± 1.4b
23.8 ± 0.9a
16:1
0.3 ± 0.05a
1.0 ± 0.2b
1.0 ± 0.1b
1.3 ± 0.2b
18:0
20.4 ± 0.3a
22.0 ± 0.5b
23.0 ± 0.4b
19.3 ± 0.2c
18:1
14.7 ± 0.4
14.3 ± 0.5
14.7 ± 1.3
14.2 ± 0.6
18:2 n-6
10.7 ± 0.4
11.0 ± 0.5
10.5 ± 1.0
10.6 ± 0.5
20:3 n-6
1.9 ± 0.1
1.6 ± 0.1
2.1 ± 0.2
1.6 ± 0.1
20:4 n-6
19.4 ± 0.9a
19.0 ± 0.7a
20.6 ± 0.7a
15.7 ± 0.7b
22:4 n-6
0.5 ± 0.1a
0.4 ± 0.05a
0.5 ± 0.1a
0.2 ± 0.02b
22:5 n-6
4.7 ± 0.5
4.1 ± 0.3
4.7 ± 0.3
3.5 ± 0.2
22:5 n-3
2.6 ± 0.2a
2.3 ± 0.2ab
2.6 ± 0.2a
1.9 ± 0.1b
22:6 n-3
4.7 ± 0.3
5.6 ± 0.5
5.0 ± 0.5
4.2 ± 0.3

Results are the means of 12 determinations ± 1 SEM expressed as μg % of total fatty acids. Fatty acids are identified by: number of carbon atoms in the chain is given first, value following the colon represents number of double bonds (zero means saturated fatty acid); number following n- indicates the position of the last double bond counting the double bond from the terminal methyl group. Values not bearing the same superscript letter are significantly different at P < 0.05.

de Gómez Dumm et al. Lipids in Health and Disease 2003 2:7   doi:10.1186/1476-511X-2-7

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