Table 2

The fatty acid composition of phospholipids from red cells from subjects with SCD and healthy controls (wt%)

Fatty acid

SCD subjects (n = 69)

Control subjects (n =72)

p-value

Saturated

C14:0

0.63 ± 0.21

0.46 ± 0.20

< 0.001

C14:1

0.10 ± 0.07

0.06 ± 0.04

< 0.001

C15:0

0.30 ± 0.17

0.21 ± 0.06

< 0.001

C16:0

30.7 ± 5.03

27.8 ± 2.44

< 0.001

C18:0

16.2 ± 2.80

15.1 ± 2.23

0.003

C20:0

0.22 ± 0.11

0.19 ± 0.06

NS

C22:0

0.22 ± 0.09

0.27 ± 0.09

< 0.001

C24:0

0.28 ± 0.16

0.38 ± 0.18

< 0.001

Monounsaturated

C16:1n-7

1.40 ± 0.67

1.43 ± 0.47

NS

C18:1n-7

2.17 ± 0.53

1.87 ± 0.36

< 0.001

C20: 1n-7

0.08 ± 0.05

0.08 ± 0.04

NS

C18:1n-9

16.5 ± 2.33

15.0 ± 1.56

< 0.001

C20:1n-9

0.34 ± 0.10

0.31 ± 0.08

0.03

C22:1n-9

0.16 ± 0.09

0.19 ± 0.06

< 0.001

C24:1

0.24 ± 0.09

0.26 ± 0.12

NS

Polyunsaturated (n-6)

C18:2n-6

10.7 ± 2.83

14.2 ± 2.41

< 0.001

C20:2n-6

0.33 ± 0.10

0.34 ± 0.08

NS

C18:3n-6

0.11 ± 0.07

0.11 ± 0.05

NS

C20:3n-6

1.44 ± 0.35

1.44 ± 0.24

NS

C20:4n-6

11.9 ± 3.94

13.0 ± 1.97

0.03

C22:4n-6

1.92 ± 0.63

1.61 ± 0.42

NS

(n-3)

C18:3n-3

0.22 ± 0.10

0.22 ± 0.07

NS

C20:5n-3

0.38 ± 0.23

0.64 ± 0.64

<0.001

C22:5n-3

0.91 ± 0.39

1.01 ± 0.24

NS

C22:6n-3

2.36 ± 1.10

3.39 ± 1.07

<0.001

NS, not significant, p > 0.05

VanderJagt et al. Lipids in Health and Disease 2003 2:2   doi:10.1186/1476-511X-2-2