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Open Access Research

Prevalence of major cardiovascular risk factors and adverse risk profiles among three ethnic groups in the Xinjiang Uygur Autonomous Region, China

Jing Tao1, Yi-tong Ma1*, Yang Xiang1, Xiang Xie1, Yi-ning Yang1, Xiao-mei Li1, Zhen-Yan Fu1, Xiang Ma1, Fen Liu2, Bang-dang Chen2, Zi-xiang Yu1 and You Chen1

Author Affiliations

1 Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P.R. China

2 Xinjiang Key Laboratory of Cardiovascular Disease Research, Urumqi 830054, P.R. China

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Lipids in Health and Disease 2013, 12:185  doi:10.1186/1476-511X-12-185

Published: 17 December 2013

Abstract

Background

Prevalence of cardiovascular disease (CVD) risk factors have been scarcely studied in Xinjiang, a multi-ethnic region.

Methods

Multi-ethnic, cross-sectional cardiovascular risk survey study in Xinjiang, including individuals of Uygur (n = 4695), Han (n = 3717) and Kazakh (n = 3196) ethnicities, aged 35-74 years. Analyses involved 11,608 participants with complete data enrolled between October 2007 and March 2010.

Results

There were differences in age-standardized prevalence of CVD risk factors between the three groups (all P < 0.001). Hypertension, obesity and smoking rates were higher among Kazakh (54.6%, 24.5%, and 35.8%, respectively). Dyslipidemia prevalence was higher among Uygur (54.3%), and diabetes prevalence was higher among Hans (7.1%). Age-standardized prevalence of adverse CVD risk profiles was different across different ethnicities. Compared with the Han participants, the Uygur and Kazakh had more CVD risk factors (P < 0.001). Compared with the Han participants, the adjusted odds ratios of 1, 2, and ≥3 risk factors profiles for Kazakh and Uygur participants were higher (all P < 0.001).

Conclusions

The present study showed the pervasive burden of CVD risk factors in all participant groups in the Xinjiang region. Three major ethnic groups living in Xinjiang had striking differences in the prevalence of major CVD risk factors and adverse risk profiles. Ethnic-specific strategies should be developed to prevent CVD in different ethnic groups, as well as to develop strategies to prevent future development of adverse CVD risk factors at a younger age.

Keywords:
Cardiovascular disease; Risk factors; Disparities; Ethnicity; Epidemiology