Table 2

Changes of body weight and serum lipid levels after six and ten weeks in different groups (mean± SD, n=6)
Control Model Fenofibrate Kaempferol-H Kaempferol-L
Bodyweight (kg)
Week 6 2.49 ± 0.22 2.82 ± 0.36 2.65 ± 0.24 2.68 ± 0.28 2.66 ± 0.25
Week 10 2.93 ± 0.15 3.24 ± 0.40 3.15 ± 0.33 3.10 ± 0.13 3.09 ± 0.24
TC (mmol/L)
Week 6 1.13 ± 0.33 6.01 ± 2.48## 2.43 ± 0.57** 1.52 ± 0.24** 2.74 ± 0.83**
Week 10 1.11 ± 0.24 9.36 ± 3.96## 4.26 ± 1.44** 2.97 ± 1.41** 3.70 ± 1.14**
TG (mmol/L)
Week 6 0.58 ± 0.16 1.80 ± 0.47## 1.09 ± 0.32** 0.85 ± 0.10** 0.88 ± 0.27**
Week 10 0.62 ± 0.1 2.26 ± 0.82## 0.88 ± 0.14** 1.39 ± 0.63* 1.30 ± 0.42*
HDL-C (mmol/L)
Week 6 0.65 ± 0.09 1.92 ± 0.57## 1.04 ± 0.24** 0.83 ± 0.16** 1.04 ± 0.21**
Week 10 0.68 ± 0.14 2.51 ± 0.74## 1.76 ± 0.67* 1.29 ± 0.57** 1.64 ± 0.37*
LDL-C (mmol/L)
Week 6 0.44 ± 0.13 3.21 ± 1.85## 1.07 ± 0.12** 0.62 ± 0.20** 1.24 ± 0.48*
Week 10 0.46 ± 0.13 3.79 ± 2.20## 1.76 ± 0.50** 1.07 ± 0.61** 1.69 ± 0.86*

Control: rabbits fed on normal diets; Model: rabbits fed on high-cholesterol diets; Fenofibrate: rabbits received high-cholesterol diets plus fenofibrate (12 mg/kg); Kaempferol-H: rabbits received high-cholesterol diets plus kaempferol (150 mg/kg); Kaempferol-L: rabbits received high-cholesterol diets plus kaempferol (30 mg/kg). TC: total cholesterol; TG: triglyceride; HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol. *P<0.05, **p < 0.01, compared with model group; ## p < 0.01, compared with control group.

Kong et al.

Kong et al. Lipids in Health and Disease 2013 12:115   doi:10.1186/1476-511X-12-115

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